Arginine Vasopressin Receptor 1B (AVPR1B) (C-Term) Peptide
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- Target See all AVPR1B products
- AVPR1B (Arginine Vasopressin Receptor 1B (AVPR1B))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- MRRRLSDGSL SSRHTTLLTR SSCPATLSLS LSLTLSGRPR PEESPRDLEL
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-AVPR1B Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- AVPR1B (Arginine Vasopressin Receptor 1B (AVPR1B))
- Synonyms
- LOC443050 Peptide, AVPR1B Peptide, si:ch211-125a15.3 Peptide, AVPR3 Peptide, V3/V1b Peptide, VIBR Peptide, VPR3 Peptide, arginine vasopressin receptor 1B Peptide, arginine vasopressin receptor 1Ab Peptide, AVPR1B Peptide, avpr1ab Peptide, Avpr1b Peptide
- Background
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The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known.
Alias Symbols: AVPR3
Protein Interaction Partner: AVP,GRK5,PRKCA
Protein Size: 424 - Molecular Weight
- 47 kDa
- Gene ID
- 553
- NCBI Accession
- NM_000707, NP_000698
- UniProt
- P47901
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