AXL Receptor tyrosine Kinase (AXL) (C-Term) Peptide
AXL
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all AXL products
- AXL (AXL Receptor tyrosine Kinase (AXL))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- QPDPKDSCSC LTAAEVHPAG RYVLCPSTTP SPAQPADRGS PAAPGQEDGA
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-AXL Antibody(ARP59004_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- AXL (AXL Receptor tyrosine Kinase (AXL))
- Synonyms
- JTK11 Peptide, UFO Peptide, AI323647 Peptide, Ark Peptide, Tyro7 Peptide, Ufo Peptide, AXL receptor tyrosine kinase Peptide, Axl receptor tyrosine kinase Peptide, AXL Peptide, Axl Peptide
- Background
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The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: JTK11, UFO
Protein Interaction Partner: AXL,GRB2,NCK2,PIK3R1,PIK3R2,PIK3R3,RANBP9,SHC1,SOCS1,TENC1,ADAM10,AXL,CBL,GAS6,GRB2,IL15RA,IL2RG,LCK,NCK2,PIK3R1,PIK3R2,PIK3R3,PLCG1,PTPN11,RANBP9,SHC1,SHC3,SOCS1,SRC,TENC1,CBL,GAS6,GRB2,LCK,PIK3R1,PIK3R2,SRC,TENC1,UBC
Protein Size: 885 - Molecular Weight
- 97 kDa
- Gene ID
- 558
- NCBI Accession
- NM_001699, NP_001690
- UniProt
- P30530
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