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Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 4 (CACNA2D4) (C-Term) Peptide

CACNA2D4 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN974359
  • Target See all CACNA2D4 products
    CACNA2D4 (Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 4 (CACNA2D4))
    Protein Region
    C-Term
    Origin
    Human
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    MAFLGTRAGL LRSSLFVGSE KVSDRKFLTP EDEASVFTLD RFPLWYRQAS
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-CACNA2D4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    CACNA2D4 (Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 4 (CACNA2D4))
    Synonyms
    cacna2d4 Peptide, cacna2d3b Peptide, si:ch211-87p6.2 Peptide, RCD4 Peptide, 5730412N02Rik Peptide, BE686333 Peptide, RGD1562038 Peptide, calcium voltage-gated channel auxiliary subunit alpha2delta 4 Peptide, calcium channel, voltage-dependent, alpha 2/delta subunit 4a Peptide, calcium channel, voltage-dependent, alpha 2/delta subunit 4b Peptide, uncharacterized LOC100630648 Peptide, calcium channel, voltage-dependent, alpha 2/delta subunit 4 Peptide, CACNA2D4 Peptide, cacna2d4a Peptide, cacna2d4b Peptide, cacna2d4 Peptide, LOC100630648 Peptide, Cacna2d4 Peptide
    Background
    This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

    Alias Symbols: RCD4

    Protein Size: 1137
    Molecular Weight
    128 kDa
    Gene ID
    93589
    NCBI Accession
    NM_172364, NP_758952
    UniProt
    Q7Z3S7
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