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CD70 Molecule (CD70) (N-Term) Peptide

CD70 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN974690
  • Target See all CD70 products
    CD70 (CD70 Molecule (CD70))
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 2
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    VICLVVCIQR FAQAQQQLPL ESLGWDVAEL QLNHTGPQQD PRLYWQGGPA
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-CD70 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    CD70 (CD70 Molecule (CD70))
    Synonyms
    CD27LG Peptide, Cd27l Peptide, Tnfsf7 Peptide, CD27L Peptide, TNFSF7 Peptide, CD70 antigen Peptide, CD70 molecule Peptide, Cd70 molecule Peptide, Cd70 Peptide, CD70 Peptide
    Background
    The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.

    Alias Symbols: CD27L, CD27LG, TNFSF7

    Protein Size: 193
    Molecular Weight
    21 kDa
    Gene ID
    970
    NCBI Accession
    NM_001252, NP_001243
    UniProt
    P32970
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