CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) Peptide
CEBPA
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all CEBPA products
- CEBPA (CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CEBPA antibody (Catalog #: P100908_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CEBPA (CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))
- Synonyms
- C/EBP-alpha Peptide, CEBP Peptide, C/ebpalpha Peptide, CBF-A Peptide, Cebp Peptide, DBPCEP Peptide, c/ebpa Peptide, cb1062 Peptide, wu:fj20f03 Peptide, C/EBP Peptide, C/EBPalpha Peptide, xC/EBP Peptide, cC/EBP Peptide, C/EBP alpha Peptide, CCAAT/enhancer binding protein alpha Peptide, CCAAT/enhancer binding protein (C/EBP), alpha Peptide, CCAAT/enhancer binding protein alpha L homeolog Peptide, CEBPA Peptide, Cebpa Peptide, cebpa Peptide, cebpa.L Peptide
- Background
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CEBPA is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. It has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, CEBPA can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.
Alias Symbols: CEBP, C/EBP-alpha
Protein Interaction Partner: LTF,NCOA6,PIAS1,ATF2,CDK2,CDK4,CDKN1A,CDKN3,CDX1,CEBPA,CEBPB,CEBPD,CREBBP,CTNNB1,DBP,EP300,GATA2,GSK3B,HNF1A,MSX2,MYC,NCOA6,NFYA,NR3C1,PIAS1,RB1,RBL1,RFC1,RUNX1,SOX10,SOX8,SPI1,SUMO3,AR,ATF2,Atf2,CDK2,CDK4,CEBPB,CTNNB1,ESR1,MAPK8,MSX2,MYC,NCOA6,NR3C1,RARB,SMAD3,SMAD4,SPI1,UBC
Protein Size: 358 - Molecular Weight
- 38 kDa
- Gene ID
- 1050
- NCBI Accession
- NM_004364, NP_004355
- UniProt
- P49715
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