Complement Factor H-Related 4 (CFHR4) (C-Term) Peptide
CFHR4
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all CFHR4 products
- CFHR4 (Complement Factor H-Related 4 (CFHR4))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- SNGEWSEPPR CIHPCIITEE NMNKNNIQLK GKSDIKYYAK TGDTIEFMCK
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CFHR4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CFHR4 (Complement Factor H-Related 4 (CFHR4))
- Synonyms
- CFHL4 Peptide, FHR-4 Peptide, FHR4 Peptide, complement factor H related 4 Peptide, CFHR4 Peptide
- Background
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This gene is a member of the complement factor H (CFH) gene family, and encodes one of the 5 CFH-related (CFHR) proteins. These 5 genes are closely linked to the CFH gene on chromosome 1q31-q32. The CFHRs are secreted plasma proteins synthesized primarily by the hepatocytes, and composed of highly-related short consensus repeats (SCRs). This protein enhances the cofactor activity of CFH, and is involved in complement regulation. It can associate with lipoproteins and may play a role in lipid metabolism. Alternatively spliced transcript variants encoding different isoforms (varying in the number of SCRs) have been described for this gene.
Alias Symbols: CFHL4, FHR-4, FHR4, RP4-608O15.2
Protein Interaction Partner: C3,CFHR4,C3,CDC42,CFHR4
Protein Size: 577 - Molecular Weight
- 63 kDa
- Gene ID
- 10877
- NCBI Accession
- NM_001201551, NP_001188480
- UniProt
- A8K9N7
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