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Collagen, Type IV, alpha 6 (COL4a6) (Middle Region) Peptide

COL4a6 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN975166
  • Target See all COL4a6 products
    COL4a6 (Collagen, Type IV, alpha 6 (COL4a6))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 4
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    GIKGKSGLPG APGFPGISGH PGKKGTRGKK GPPGSIVKKG LPGLKGLPGN
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-COL4A6 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    COL4a6 (Collagen, Type IV, alpha 6 (COL4a6))
    Synonyms
    CXDELq22.3 Peptide, DELXq22.3 Peptide, BB116301 Peptide, collagen type IV alpha 6 chain Peptide, collagen, type IV, alpha 6 Peptide, COL4A6 Peptide, Col4a6 Peptide, col4a6 Peptide
    Background
    This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene, alpha 5 type IV collagen, so that the gene pair shares a common promoter. Deletions in the alpha 5 gene that extend into the alpha 6 gene result in diffuse leiomyomatosis accompanying the X-linked Alport syndrome caused by the deletion in the alpha 5 gene. Two splice variants have been identified for this gene.

    Alias Symbols: MGC88184, DELXq22.3, CXDELq22.3

    Protein Interaction Partner: APP,CD93,DCN,FBLN2,FN1,HABP2,MATN2,MMP9,OSM,SERPINE2

    Protein Size: 1691
    Molecular Weight
    161 kDa
    Gene ID
    1288
    NCBI Accession
    NM_001847, NP_001838
    UniProt
    Q14031
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