COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5) Peptide
COPS5
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all COPS5 products
- COPS5 (COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-COPS5 antibody (Catalog #: ARP32834_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- COPS5 (COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5))
- Synonyms
- BcDNA.LD14392 Peptide, BcDNA:LD14392 Peptide, CG14884 Peptide, CH5 Peptide, CSN-5 Peptide, Csn5 Peptide, DCH5 Peptide, Dch5 Peptide, Dmel\\CG14884 Peptide, JAB1 Peptide, JAB1/CSN5 Peptide, Jab1 Peptide, JadBp Peptide, csn5 Peptide, dch5 Peptide, jab1/csn5 Peptide, l(3)89Cf Peptide, l(3)L4032 Peptide, l(3)M203 Peptide, quo Peptide, COPS5 Peptide, MGC76063 Peptide, AI303502 Peptide, CSN5 Peptide, Mov34 Peptide, Sgn5 Peptide, zgc:73130 Peptide, MOV-34 Peptide, SGN5 Peptide, COP9 signalosome subunit 5 Peptide, COP9 signalosome complex subunit 5 Peptide, COP9 signalosome subunit 5 S homeolog Peptide, CSN5 Peptide, COPS5 Peptide, cops5 Peptide, CpipJ_CPIJ012314 Peptide, Bm1_46585 Peptide, VDBG_06932 Peptide, LOAG_01443 Peptide, csn5 Peptide, Cops5 Peptide, cops5.S Peptide, csn-5 Peptide
- Background
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The protein encoded by COPS5 is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors.
Alias Symbols: CSN5, JAB1, SGN5, MOV-34
Protein Interaction Partner: HIF1A,CDKN1B,COPS6,S100A7,BCL3,CDKN1B,COPS2,COPS3,COPS4,COPS6,COPS7A,COPS8,CUL5,ERN1,ESR1,F2RL1,GFER,GFI1B,GPS1,HAND2,HIF1A,HNF4A,HNF4G,JUN,JUND,MIF,NCOA1,NR4A2,NR4A3,PPARG,RNF139,RORA,S100A7,SMAD2,SMAD4,TP53,TXN,UCHL1,BCL3,BTBD2,CDKN1B,COPS2,COPS3,COPS4,COPS6,COPS7A,COPS7B,COPS8,CPSF1,CUL1,CUL2,CUL3,CUL4A,CUL4B,DCAF11,DCAF4,DDB1,DDB2,ERCC8,FBXO11,FBXO17,FBXO22,GFER,GPS1,HAND2,JUN,JUND,KLHL13,KLHL15,KLHL18,KLHL22,KLHL24,KLHL9,LRRC14,MAPRE1,MDM2,MIF,NEDD8,PPIL5,PTGS2,S100A7,SAP130,SKP2,SMAD4,TOR1AIP2,TP53,TRAF2,UCHL1,UCHL3,VPRBP
Protein Size: 334 - Molecular Weight
- 38 kDa
- Gene ID
- 10987
- NCBI Accession
- NM_006837, NP_006828
- UniProt
- Q92905
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