COP9 Signalosome Subunit 8 (COPS8) (Middle Region) Peptide
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- Target See all COPS8 products
- COPS8 (COP9 Signalosome Subunit 8 (COPS8))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- TRMVLPRKPV AGALDVSFNK FIPLSEPAPV PPIPNEQQLA RLTDYVAFLE
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-COPS8 Antibody(ARP52242_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- COPS8 (COP9 Signalosome Subunit 8 (COPS8))
- Synonyms
- COP9 Peptide, CSN8 Peptide, SGN8 Peptide, csn8 Peptide, cops8 Peptide, MGC76051 Peptide, MGC80215 Peptide, DDBDRAFT_0167123 Peptide, DDBDRAFT_0233107 Peptide, DDB_0167123 Peptide, DDB_0233107 Peptide, zgc:56319 Peptide, zgc:86840 Peptide, MGC86182 Peptide, 9430009J09Rik Peptide, AA408242 Peptide, Csn8 Peptide, Sgn8 Peptide, CONSTITUTIVE PHOTOMORPHOGENIC 9 Peptide, COP9 SIGNALOSOME SUBUNIT 8 Peptide, DL3095C Peptide, EMB143 Peptide, EMBRYO DEFECTIVE 143 Peptide, FCAALL.131 Peptide, FUS7 Peptide, FUSCA 7 Peptide, FUSCA PROTEIN FUS7 Peptide, CG13383 Peptide, CG33297 Peptide, CG42522 Peptide, CH8 Peptide, Dch8 Peptide, Dmel\\CG42522 Peptide, Dmel_CG13383 Peptide, l(2)SH1829 Peptide, l(2)SH2 1829 Peptide, COP9 signalosome subunit 8 Peptide, COP9 signalosome subunit 8 S homeolog Peptide, COP9 signalosome complex subunit 8 Peptide, COP9 signalosome subunit 8 L homeolog Peptide, COP9 signalosome, subunit CSN8 Peptide, COPS8 Peptide, Cops8 Peptide, cops8 Peptide, cops8.S Peptide, CSN8 Peptide, csn8 Peptide, cops8.L Peptide, COP9 Peptide
- Background
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The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Alias Symbols: COP9, CSN8, MGC1297, MGC43256, SGN8
Protein Interaction Partner: COPS3,COPS4,COPS8,COPS2,COPS3,COPS4,COPS5,COPS6,COPS7A,COPS8,CUL5,EIF3E,GPS1,ITPK1,NFKBIA,TP53,COPS2,COPS3,COPS4,COPS5,COPS6,COPS7A,COPS7B,COPS8,CUL1,CUL4A,DDB1,GPS1,MAPRE1,RAE1
Protein Size: 209 - Molecular Weight
- 23 kDa
- Gene ID
- 10920
- NCBI Accession
- NM_006710, NP_006701
- UniProt
- Q99627
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