Corticotropin Releasing Hormone Receptor 1 (CRHR1) (C-Term) Peptide
CRHR1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all CRHR1 products
- CRHR1 (Corticotropin Releasing Hormone Receptor 1 (CRHR1))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- RPGVYTDYIY QGPMILVLLI NFIFLFNIVR ILMTKLRAST TSETIQYRKA
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CRHR1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CRHR1 (Corticotropin Releasing Hormone Receptor 1 (CRHR1))
- Synonyms
- CRF-R Peptide, CRF-R-1 Peptide, CRF-R1 Peptide, CRF1 Peptide, CRFR-1 Peptide, CRFR1 Peptide, CRH-R-1 Peptide, CRH-R1 Peptide, CRH-R1h Peptide, CRHR Peptide, CRHR1L Peptide, CRHR1f Peptide, Crhr Peptide, crhr1 Peptide, crhr1-A Peptide, CRHR1 Peptide, CRHR1-IT1-CRHR1 Peptide, MGC57346-CRHR1 Peptide, corticotropin releasing hormone receptor 1 Peptide, corticotropin releasing hormone receptor 1, gene 2 S homeolog Peptide, corticotropin-releasing factor receptor 1 Peptide, LINC02210-CRHR1 readthrough Peptide, CRHR1 Peptide, Crhr1 Peptide, crhr1.2.S Peptide, LOC610380 Peptide, LOC100065598 Peptide, LINC02210-CRHR1 Peptide, crhr1 Peptide
- Background
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This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants one of which is a non-coding read-through transcript with the neighboring gene MGC57346.
Alias Symbols: CRF-R, CRF1, CRFR1, CRH-R1h, CRHR, CRHR1L, CRHR1f, CRF-R1, CRFR-1, CRH-R1, CRF-R-1, CRH-R-1
Protein Interaction Partner: CALM1,CALM1,CRH,GNAI1,GNAO1,GNAQ,GNAS,UCN,UCN3,CRH,GNAI1,GNAO1,GNAQ,GNAS,UCN,Ucn
Protein Size: 401 - Molecular Weight
- 44 kDa
- Gene ID
- 1394
- NCBI Accession
- NM_001145148, NP_001138620
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