Corticotropin Releasing Hormone Receptor 2 (CRHR2) (N-Term) Peptide
CRHR2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all CRHR2 products
- CRHR2 (Corticotropin Releasing Hormone Receptor 2 (CRHR2))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- NTTLDQIGTC WPRSAAGALV ERPCPEYFNG VKYNTTRNAY RECLENGTWA
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CRHR2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CRHR2 (Corticotropin Releasing Hormone Receptor 2 (CRHR2))
- Synonyms
- CRF-RB Peptide, CRF2 Peptide, CRFR2 Peptide, HM-CRF Peptide, CRF-R2 Peptide, CRFR2alpha Peptide, CRFR2beta Peptide, Crfr2 Peptide, Crf2r Peptide, CRH-R2 Peptide, crhr2-A Peptide, corticotropin releasing hormone receptor 2 Peptide, corticotropin releasing hormone receptor 2 S homeolog Peptide, CRHR2 Peptide, Crhr2 Peptide, crhr2.S Peptide
- Background
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The protein encoded by this gene belongs to the G-protein coupled receptor 2 family, and the subfamily of corticotropin releasing hormone receptor. This receptor shows high affinity for corticotropin releasing hormone (CRH), and also binds CRH-related peptides such as urocortin. CRH is synthesized in the hypothalamus, and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress and immune challenge. Studies in mice suggest that this receptor maybe involved in mediating cardiovascular homeostasis.
Alias Symbols: CRFR2, CRF2, CRF-RB, HM-CRF
Protein Size: 438 - Molecular Weight
- 48 kDa
- Gene ID
- 1395
- NCBI Accession
- NM_001202475, NP_001189404
- UniProt
- Q13324
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