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Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1) Peptide

CXCL1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN975472
  • Target See all CXCL1 products
    CXCL1 (Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1))
    Origin
    Human
    Source
    • 5
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-CXCL1 antibody (Catalog #: AVARP07032_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    CXCL1 (Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1))
    Synonyms
    FSP Peptide, GRO1 Peptide, GROa Peptide, MGSA Peptide, MGSA-a Peptide, NAP-3 Peptide, SCYB1 Peptide, CINC-1 Peptide, Gro1 Peptide, CXCL1 Peptide, Sdf1 Peptide, Fsp Peptide, KC Peptide, Mgsa Peptide, N51 Peptide, Scyb1 Peptide, gro Peptide, GRO Peptide, Gro Peptide, C-X-C motif chemokine ligand 1 Peptide, chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) Peptide, C-X-C motif chemokine ligand 12 Peptide, chemokine (C-X-C motif) ligand 1 Peptide, CXCL1 Peptide, Cxcl1 Peptide, Cxcl12 Peptide, GRO1 Peptide
    Background
    Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues, the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CXC chemokines are further subdivided into ELR and non-ELR types based on the presence or absence of a glu-leu-arg sequence adjacent and N terminal to the CXC motif.Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues, the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CXC chemokines are further subdivided into ELR and non-ELR types based on the presence or absence of a glu-leu-arg sequence adjacent and N terminal to the CXC motif.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: GRO1, GROa, MGSA, MGSA alpha, MGSA-a, NAP-3, SCYB1, FSP

    Protein Interaction Partner: CXCR1,CXCL1,CXCR1,CXCR2,DARC,MMP9,CXCL1,DARC

    Protein Size: 107
    Molecular Weight
    8 kDa
    Gene ID
    2919
    NCBI Accession
    NM_001511, NP_001502
    UniProt
    P09341
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