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Decorin (DCN) Peptide

DCN Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN975627
  • Target See all Decorin (DCN) products
    Decorin (DCN)
    Origin
    Human
    Source
    • 5
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-DCN antibody (Catalog #: ARP48200_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    Decorin (DCN)
    Synonyms
    CSCD Peptide, DSPG2 Peptide, PG40 Peptide, PGII Peptide, PGS2 Peptide, SLRR1B Peptide, DC Peptide, mDcn Peptide, cscd Peptide, dspg2 Peptide, pg40 Peptide, pgii Peptide, pgs2 Peptide, slrr1b Peptide, decorin Peptide, decorin L homeolog Peptide, DCN Peptide, Dcn Peptide, dcn.L Peptide, dcn Peptide
    Background
    DCN is a small cellular or pericellular matrix proteoglycan that is closely related in structure to biglycan protein. DCN and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. It contains one attached glycosaminoglycan chain. This protein is capable of suppressing the growth of various tumor cell lines. There are multiple alternatively spliced transcript variants known for this gene. This gene is a candidate gene for Marfan syndrome.The protein encoded by this gene is a small cellular or pericellular matrix proteoglycan that is closely related in structure to biglycan protein. The encoded protein and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. It contains one attached glycosaminoglycan chain. This protein is capable of suppressing the growth of various tumor cell lines. There are multiple alternatively spliced transcript variants known for this gene. This gene is a candidate gene for Marfan syndrome.

    Alias Symbols: CSCD, DSPG2, PG40, PGII, PGS2, SLRR1B

    Protein Interaction Partner: AHSG,C1QA,COL14A1,COL1A1,COL1A2,COL4A1,COL4A3,COL4A4,COL4A5,COL4A6,COL5A1,DPT,EGFR,ELN,FBN1,FLNA,FN1,MMP2,MMP3,MMP7,PLA2G2A,SFTPD,TGFB1,THBS1,TNF,WISP1,AHSG,C1QA,COL14A1,COL6A1,EGFR,ELN,FLNA,PLA2G2A,SFTPD,TGFB1,TGFB2,TNF

    Protein Size: 359
    Molecular Weight
    36 kDa
    Gene ID
    1634
    NCBI Accession
    NM_001920, NP_001911
    UniProt
    P07585
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