Dolichyl-diphosphooligosaccharide--Protein Glycosyltransferase (DDOST) Peptide
DDOST
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all DDOST products
- DDOST (Dolichyl-diphosphooligosaccharide--Protein Glycosyltransferase (DDOST))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-DDOST antibody (Catalog #: ARP46585_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- DDOST (Dolichyl-diphosphooligosaccharide--Protein Glycosyltransferase (DDOST))
- Synonyms
- AGER1 Peptide, CDG1R Peptide, OKSWcl45 Peptide, OST Peptide, OST48 Peptide, WBP1 Peptide, DDOST Peptide, wu:fa11d01 Peptide, zgc:66068 Peptide, zgc:77478 Peptide, Ddost Peptide, CG9022 Peptide, DmOST50 Peptide, Dmel\\CG9022 Peptide, DrOST Peptide, OST48/WBP1 Peptide, Ots48 Peptide, anon-EST:Liang-1.11 Peptide, clone 1.11 Peptide, ost48 Peptide, dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit Peptide, dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) S homeolog Peptide, dolichyl-diphosphooligosaccharide-protein glycosyltransferase Peptide, dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) Peptide, dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit Peptide, dolichyl-di-phosphooligosaccharide-protein glycotransferase Peptide, Oligosaccharyltransferase 48kD subunit Peptide, DDOST Peptide, ddost.S Peptide, GTR26 Peptide, ddost Peptide, Ddost Peptide, LOC5580056 Peptide, PTRG_01946 Peptide, Ost48 Peptide
- Background
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DDOST is a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. DDOST is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia.
Alias Symbols: AGE-R1, KIAA0115, MGC2191, OK/SW-cl.45, OST, OST48, WBP1, AGER1, OKSWcl45
Protein Interaction Partner: BRCC3,GSTK1,MAGEA6,PGRMC1,RFXANK,SAP18,TMBIM4
Protein Size: 456 - Molecular Weight
- 46 kDa
- Gene ID
- 1650
- NCBI Accession
- NM_005216, NP_005207
- UniProt
- Q5VWA5
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