2,4-Dienoyl CoA Reductase 2, Peroxisomal (DECR2) (C-Term) Peptide
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- Target See all DECR2 products
- DECR2 (2,4-Dienoyl CoA Reductase 2, Peroxisomal (DECR2))
- Protein Region
- C-Term
- Origin
- Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- PIPRLGTKTE IAHSVLYLAS PLASYVSGIV LVVDGGSWMT FPNGIKQLLE
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Decr2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- DECR2 (2,4-Dienoyl CoA Reductase 2, Peroxisomal (DECR2))
- Synonyms
- PDCR Peptide, SDR17C1 Peptide, zC153C20.5 Peptide, zgc:85626 Peptide, Dcrakl Peptide, putativeperoxisomal24-dienoyl-CoAreductase Peptide, 2,4-dienoyl-CoA reductase 2 Peptide, 2,4-dienoyl CoA reductase 2, peroxisomal Peptide, 2,4-dienoyl-CoA reductase 2 L homeolog Peptide, 2-4-dienoyl-Coenzyme A reductase 2, peroxisomal Peptide, DECR2 Peptide, decr2 Peptide, decr2.L Peptide, Decr2 Peptide
- Background
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Decr2 is the auxiliary enzyme of beta-oxidation. Decr2 participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Decr2 catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Decr2 has activity towards short and medium chain 2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19-docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid.
Alias Symbols: -
Protein Size: 292 - Molecular Weight
- 31 kDa
- Gene ID
- 26378
- NCBI Accession
- NM_011933, NP_036063
- UniProt
- Q9WV68
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