Docking Protein 7 (DOK7) (C-Term) Peptide
DOK7
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all DOK7 products
- DOK7 (Docking Protein 7 (DOK7))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- RAHYDTPRSL CLAPRDHSPP SQGSPGNSAA RDSGGQTSAG CPSGWLGTRR
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-DOK7 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- DOK7 (Docking Protein 7 (DOK7))
- Synonyms
- si:dkey-180b4.3 Peptide, si:ch211-164d19.2 Peptide, C4orf25 Peptide, CMS1B Peptide, A930013K19Rik Peptide, AW049091 Peptide, Dok-7 Peptide, EF-12 Peptide, Oit5 Peptide, RGD1566416 Peptide, dok-7 Peptide, docking protein 7 Peptide, DOK7 Peptide, dok7 Peptide, Dok7 Peptide
- Background
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The protein encoded by this gene is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase. Mutations in this gene are a cause of familial limb-girdle myasthenia autosomal recessive, which is also known as congenital myasthenic syndrome type 1B.
Alias Symbols: C4orf25, CMS1B, FLJ33718, FLJ39137, FLJ90556
Protein Interaction Partner: MUSK
Protein Size: 366 - Molecular Weight
- 40 kDa
- Gene ID
- 285489
- NCBI Accession
- NM_173660, NP_775931
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