Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2) (Middle Region) Peptide
EIF2AK2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all EIF2AK2 products
- EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- QVFKAKHRID GKTYVIKRVK YNNEKAEREV KALAKLDHVN IVHYNGCWDG
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-EIF2AK2 Antibody(ARP36709_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))
- Synonyms
- PKR Peptide, pkr Peptide, EIF2AK2 Peptide, DKFZp469K1934 Peptide, EIF2AK1 Peptide, PRKR Peptide, 2310047A08Rik Peptide, 4732414G15Rik Peptide, AI467567 Peptide, AI747578 Peptide, Pkr Peptide, Prkr Peptide, Tik Peptide, eukaryotic translation initiation factor 2 alpha kinase 2 Peptide, eukaryotic translation initiation factor 2-alpha kinase 2 Peptide, EIF2AK2 Peptide, eif2ak2 Peptide, Eif2ak2 Peptide
- Background
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EIF2AK2 might play a role in ER stress-induced apoptosis and in Alzheimer's disease. Alzheimer cases show prominent EIF2AK2 activation in association with neuritic plaques and pyramidal neurons in the hippocampus and neocortex.
Alias Symbols: EIF2AK1, MGC126524, PKR, PRKR
Protein Interaction Partner: EIF2S1,HIV2gp5,HTT,PRKRA,tat,CASP3,CASP7,CASP8,CDC42,CHUK,DNAJC3,EIF2AK2,EIF2S1,ELF2,HSP90AA1,HSPA1A,IKBKB,ILF3,JAK1,MAP3K5,MAP3K7,METAP2,NFKBIA,NPM1,PDGFRB,PPP1CA,PPP1CC,PPP2R5A,PRKRA,PRKRIP1,PRKRIR,PTGES3,RAC1,STAT1,STAT3,STRBP,TAB2,TARBP2,TIRAP,TP53,TY
Protein Size: 551 - Molecular Weight
- 62 kDa
- Gene ID
- 5610
- NCBI Accession
- NM_002759, NP_002750
- UniProt
- P19525
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