Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) Peptide
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- Target See all EIF2S1 products
- EIF2S1 (Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-EIF2S1 antibody (Catalog #: ARP40508_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- EIF2S1 (Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1))
- Synonyms
- EIF-2 Peptide, EIF-2A Peptide, EIF-2alpha Peptide, EIF2 Peptide, EIF2A Peptide, Eif2s1 Peptide, eif2s1l Peptide, fb36a08 Peptide, wu:fb36a08 Peptide, zgc:56510 Peptide, 0910001O23Rik Peptide, 2410026C18Rik Peptide, 35kDa Peptide, Eif2a Peptide, eIF2alpha Peptide, eif2a Peptide, CG9946 Peptide, Dmel\\CG9946 Peptide, Eif2alpha Peptide, IF2A_DROME Peptide, M(1)14C Peptide, M(1)19-153 Peptide, M(1)8e3-10 Peptide, deIF2alpha Peptide, eIF-2 Peptide, eIF-2 a Peptide, eIF-2 alpha Peptide, eIF2 alpha Peptide, eIF2-alpha Peptide, eIF2a Peptide, eiF-2alpha Peptide, elF2alpha Peptide, l(1)14Cf Peptide, l(1)19-153 Peptide, eukaryotic translation initiation factor 2 subunit alpha Peptide, eukaryotic translation initiation factor 2, subunit 1 alpha a Peptide, eukaryotic translation initiation factor 2, subunit 1 alpha Peptide, eukaryotic translation initiation factor 2 alpha subunit Peptide, Eukaryotic translation initiation factor 2 subunit 1 Peptide, eukaryotic translation initiation factor 2 subunit alpha L homeolog Peptide, eukaryotic translation Initiation Factor 2alpha Peptide, EIF2S1 Peptide, eif2s1a Peptide, Eif2s1 Peptide, eif2s1 Peptide, LOC693063 Peptide, CNI00230 Peptide, THAPSDRAFT_105 Peptide, if2a Peptide, eif2s1.L Peptide, eIF-2alpha Peptide
- Background
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The translation initiation factor eIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, eIF2, and GTP. eIF2 is composed of 3 nonidentical subunits, alpha (36 kD), beta (38 kD), and gamma (52 kD). The rate of formation of the ternary complex is modulated by the phosphorylation state of eIF2-alpha.The translation initiation factor eIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, eIF2, and GTP. eIF2 is composed of 3 nonidentical subunits, alpha (36 kD), beta (38 kD, MIM 603908), and gamma (52 kD, MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of eIF2-alpha (Ernst et al., 1987).[supplied by OMIM].
Alias Symbols: EIF-2, EIF-2A, EIF-2alpha, EIF2, EIF2A
Protein Interaction Partner: EIF2AK2,CASP3,CASP6,EIF1AX,EIF2AK1,EIF2AK2,EIF2AK3,EIF2B1,EIF2B2,EIF2B3,EIF2B4,EIF2S2,MELK,P4HB,PPP1R15A,PRKCD,PRKRIR,SFN,EIF1B,EIF2B1,PPP1R15A
Protein Size: 315 - Molecular Weight
- 35 kDa
- Gene ID
- 1965
- NCBI Accession
- NM_004094, NP_004085
- UniProt
- P05198
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