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Eukaryotic Translation Initiation Factor 3, Subunit D (EIF3D) (N-Term) Peptide

EIF3D Reactivity: Human, Rat Host: Synthetic BP, WB
Catalog No. ABIN976221
  • Target See all EIF3D products
    EIF3D (Eukaryotic Translation Initiation Factor 3, Subunit D (EIF3D))
    Protein Region
    N-Term
    Origin
    Human, Rat
    Source
    • 2
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    SGWGPCAVPE QFRDMPYQPF SKGDRLGKVA DWTGATYQDK RYTNKYSSQF
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-Eif3d Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    EIF3D (Eukaryotic Translation Initiation Factor 3, Subunit D (EIF3D))
    Synonyms
    eif3s7 Peptide, eIF3d Peptide, DDBDRAFT_0217568 Peptide, DDBDRAFT_0219927 Peptide, DDB_0217568 Peptide, DDB_0219927 Peptide, EIF3S7 Peptide, An15g03780 Peptide, AO090026000811 Peptide, eIF3-p66 Peptide, eIF3-zeta Peptide, 66/67kDa Peptide, AA407891 Peptide, Eif3s7 Peptide, eIF3p66 Peptide, wu:fb12a03 Peptide, zgc:64097 Peptide, eukaryotic translation initiation factor 3 subunit D Peptide, eukaryotic translation initiation factor 3 subunit 7 Peptide, eukaryotic initiation factor Peptide, eIF-3 zeta Peptide, eukaryotic translation initiation factor 3, subunit D Peptide, translation initiation factor eIF-3 subunit 7 Peptide, eukaryotic translation initiation factor 3 subunit D S homeolog Peptide, Eukaryotic translation initiation factor 3 subunit D Peptide, eif3d Peptide, EIF3D Peptide, eIF3-S7 Peptide, ANI_1_540134 Peptide, AOR_1_1456014 Peptide, PTRG_07832 Peptide, VDBG_06053 Peptide, PGTG_10613 Peptide, Tsp_00484 Peptide, Eif3d Peptide, eif3d.S Peptide, eif-3.D Peptide
    Background
    Eif3d is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.

    Alias Symbols: Eif3s7, MGC93918

    Protein Size: 548
    Molecular Weight
    60 kDa
    Gene ID
    362952
    NCBI Accession
    NM_001004283, NP_001004283
    UniProt
    Q6AYK8
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