Estrogen-Related Receptor alpha (ESRRA) (C-Term) Peptide
ESRRA
Reactivity: Mouse
Host: Synthetic
BP, WB
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- Target See all ESRRA products
- ESRRA (Estrogen-Related Receptor alpha (ESRRA))
- Protein Region
- C-Term
- Origin
- Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- AGRAGPGGGA ERRRAGRLLL TLPLLRQTAG KVLAHFYGVK LEGKVPMHKL
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Esrra Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ESRRA (Estrogen-Related Receptor alpha (ESRRA))
- Synonyms
- err1 Peptide, erra Peptide, esrral Peptide, erralpha Peptide, nr3b1 Peptide, MGC80854 Peptide, ESRRA Peptide, esrl1 Peptide, LOC100125507 Peptide, ERRalpha Peptide, Err1 Peptide, Estrra Peptide, Nr3b1 Peptide, Errra Peptide, ERR1 Peptide, ERRa Peptide, ESRL1 Peptide, NR3B1 Peptide, ESTRRA Peptide, estrogen-related receptor alpha Peptide, estrogen related receptor alpha L homeolog Peptide, estrogen related receptor alpha Peptide, catsper channel auxiliary subunit zeta Peptide, estrogen related receptor, alpha Peptide, esrra Peptide, esrra.L Peptide, ESRRA Peptide, LOC100125507 Peptide, CATSPERZ Peptide, Esrra Peptide
- Background
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Esrra binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. It can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. It binds to the C1 region of the lactoferrin gene promoter. It requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism.
Alias Symbols: ERRalpha, Err1, Estrra, Nr3b1
Protein Interaction Partner: Crebzf,Esrrb,Hdac8,Kat2b,Ppargc1a,Sirt1
Protein Size: 422 - Molecular Weight
- 45 kDa
- Gene ID
- 26379
- NCBI Accession
- NM_007953, NP_031979
- UniProt
- O08580
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