Eyes Absent Homolog 4 (EYA4) (N-Term) Peptide
EYA4
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all EYA4 products
- EYA4 (Eyes Absent Homolog 4 (EYA4))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- YLLNEPGVQP TSVYGDFSCK EEPEIDSPGG DIGLSLQRVF TDLKNMDATW
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-IRF1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- EYA4 (Eyes Absent Homolog 4 (EYA4))
- Synonyms
- B130023L16Rik Peptide, CMD1J Peptide, DFNA10 Peptide, EYA transcriptional coactivator and phosphatase 4 Peptide, Eya4 Peptide, EYA4 Peptide
- Background
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IRF1 is interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion.
Alias Symbols: IRF-1, MAR
Protein Interaction Partner: CSNK2A1,CSNK2B,CTDP1,DR1,DRAP1,ERCC3,GTF2F1,MED23,POLR2D,POLR2D,SUB1,TBP,E6,EP300,HMGA1,IRF8,KAT2B,NFKB1,RELA,STAT1,CREBBP,EP300,HMGA1,IRF8,IRF9,KAT2A,KAT2B,SMARCA4,STAT1,STUB1,UBC,tat
Protein Size: 325 - Molecular Weight
- 36 kDa
- Gene ID
- 3659
- NCBI Accession
- NM_002198, NP_002189
- UniProt
- P10914
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