F-Box Protein 32 (FBXO32) (N-Term) Peptide
FBXO32
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all FBXO32 products
- FBXO32 (F-Box Protein 32 (FBXO32))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- QQQLNNIQIT RPAFKGLTFT DLPLCLQLNI MQRLSDGRDL VSLGQAAPDL
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-FBXO32 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- FBXO32 (F-Box Protein 32 (FBXO32))
- Synonyms
- MGC56479 Peptide, zgc:56479 Peptide, Fbx32 Peptide, MAFbx Peptide, 4833442G10Rik Peptide, AI430017 Peptide, ATROGIN1 Peptide, Gm20361 Peptide, Atrogin1 Peptide, F-box protein 32 Peptide, fbxo32 Peptide, FBXO32 Peptide, Fbxo32 Peptide
- Background
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This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing of this gene results in two transcript variants encoding two isoforms of different sizes.
Alias Symbols: FLJ32424, Fbx32, MAFbx, MGC33610
Protein Interaction Partner: SKP1,EIF3A,SKP1
Protein Size: 210 - Molecular Weight
- 25 kDa
- Gene ID
- 114907
- NCBI Accession
- NM_148177, NP_680482
- UniProt
- Q0VAQ6
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