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Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B) (C-Term) Peptide

FCGR2B Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN976783
  • Target See all FCGR2B products
    FCGR2B (Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B))
    Protein Region
    C-Term
    Origin
    Human
    Source
    • 4
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    CREMGETLPE KPANPTNPDE ADKVGAENTI TYSLLMHPDA LEEPDDQNRI
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-FCGR2B Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    FCGR2B (Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B))
    Synonyms
    CD32 Peptide, CD32B Peptide, FCG2 Peptide, FCGR2 Peptide, IGFR2 Peptide, FCGR2B Peptide, AI528646 Peptide, F630109E10Rik Peptide, Fc[g]RII Peptide, FcgRII Peptide, Fcgr2 Peptide, Fcgr2a Peptide, Fcr-2 Peptide, Fcr-3 Peptide, Ly-17 Peptide, Ly-m20 Peptide, LyM-1 Peptide, Lym-1 Peptide, FCRII Peptide, FcRII Peptide, Fc fragment of IgG receptor IIb Peptide, Fc fragment of IgG, low affinity IIb, receptor (CD32) Peptide, Fc receptor, IgG, low affinity IIb Peptide, low affinity immunoglobulin gamma Fc region receptor II Peptide, FCGR2B Peptide, Fcgr2b Peptide, LOC100856270 Peptide
    Background
    The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: CD32, CD32B, FCG2, FCGR2, IGFR2

    Protein Interaction Partner: APCS,BLK,C14orf1,CRP,INPP5D,INPPL1,LY6E,LYN,MAPK1,MAPK3,PTPN6,PTPN11,SHC1

    Protein Size: 310
    Molecular Weight
    34 kDa
    Gene ID
    2213
    NCBI Accession
    NM_001002275, NP_001002275
    UniProt
    P31994
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