Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B) (C-Term) Peptide
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- Target See all FCGR2B products
- FCGR2B (Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- CREMGETLPE KPANPTNPDE ADKVGAENTI TYSLLMHPDA LEEPDDQNRI
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-FCGR2B Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- FCGR2B (Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B))
- Synonyms
- CD32 Peptide, CD32B Peptide, FCG2 Peptide, FCGR2 Peptide, IGFR2 Peptide, FCGR2B Peptide, AI528646 Peptide, F630109E10Rik Peptide, Fc[g]RII Peptide, FcgRII Peptide, Fcgr2 Peptide, Fcgr2a Peptide, Fcr-2 Peptide, Fcr-3 Peptide, Ly-17 Peptide, Ly-m20 Peptide, LyM-1 Peptide, Lym-1 Peptide, FCRII Peptide, FcRII Peptide, Fc fragment of IgG receptor IIb Peptide, Fc fragment of IgG, low affinity IIb, receptor (CD32) Peptide, Fc receptor, IgG, low affinity IIb Peptide, low affinity immunoglobulin gamma Fc region receptor II Peptide, FCGR2B Peptide, Fcgr2b Peptide, LOC100856270 Peptide
- Background
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The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CD32, CD32B, FCG2, FCGR2, IGFR2
Protein Interaction Partner: APCS,BLK,C14orf1,CRP,INPP5D,INPPL1,LY6E,LYN,MAPK1,MAPK3,PTPN6,PTPN11,SHC1
Protein Size: 310 - Molecular Weight
- 34 kDa
- Gene ID
- 2213
- NCBI Accession
- NM_001002275, NP_001002275
- UniProt
- P31994
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