Forkhead Box A3 (FOXA3) (C-Term) Peptide
FOXA3
Reactivity: Mouse
Host: Synthetic
BP, WB
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- Target See all FOXA3 products
- FOXA3 (Forkhead Box A3 (FOXA3))
- Protein Region
- C-Term
- Origin
- Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- YNFNHPFSIN NLMSEQTSTP SKLDVGFGGY GAESGEPGVY YQSLYSRSLL
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Foxa3 Antibody(ARP36881_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- FOXA3 (Forkhead Box A3 (FOXA3))
- Synonyms
- FOXA3 Peptide, Zffkh1 Peptide, fa11c04 Peptide, fkd2 Peptide, forkhead-2 Peptide, wu:fa11c04 Peptide, wu:fc37a08 Peptide, zf-FKH1 Peptide, FKHH3 Peptide, HNF3G Peptide, TCF3G Peptide, HNF3-G Peptide, Hnf-3g Peptide, Hnf3g Peptide, Tcf-3g Peptide, Tcf3g Peptide, forkhead box A3 Peptide, FOXA3 Peptide, foxa3 Peptide, Foxa3 Peptide
- Background
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Foxa3 is a transcription factor that is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Foxa3 is originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Foxa3 interacts with the cis-acting regulatory regions of these genes.Foxa3 is involved in glucose homeostasis, activates GLUT2 transcription and regulation of neuronal-specific transcription. Foxa3 is also involved in regulation of spermatogenesis, required for the maintenance of the testicular germ cell population and male fertility.
Alias Symbols: Hnf-3g, Hnf3g, Tcf-3g, Tcf3g
Protein Size: 353 - Molecular Weight
- 37 kDa
- Gene ID
- 15377
- NCBI Accession
- NM_008260, NP_032286
- UniProt
- P35584
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