Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) (N-Term) Peptide
HIF1A
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all HIF1A products
- HIF1A (Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-HIF1A antibody (Catalog #: AVARP20009_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) (AA 530-826) peptide
HIF1A Reactivity: Human Host: Escherichia coli (E. coli) SDS Dithiothreitol (DTT)
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- HIF1A (Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A))
- Synonyms
- hif1a Peptide, AA959795 Peptide, HIF1alpha Peptide, MOP1 Peptide, bHLHe78 Peptide, HIF-1A Peptide, HIF-1alpha Peptide, HIF1 Peptide, HIF1-ALPHA Peptide, PASD8 Peptide, HIF1-alpha Peptide, hif-1a Peptide, hypoxia inducible factor 1 alpha Peptide, hypoxia inducible factor 1, alpha subunit Peptide, hypoxia inducible factor 1 alpha subunit Peptide, HIF (Hypoxia Inducible Factor) homologa Peptide, hif-1a Peptide, Hif1a Peptide, HIF1A Peptide, hif1a Peptide, hif-1 Peptide
- Background
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Hypoxia-inducible factor-1 (HIF1) is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has been identified as the aryl hydrocarbon receptor nuclear translocator (ARNT). HIF1A is the alpha subunit of HIF-1. Overexpression of a natural antisense transcript (aHIF) of this gene has been shown to be associated with nonpapillary renal carcinomas. Two alternative transcripts encoding different isoforms have been identified.
Alias Symbols: HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78
Protein Interaction Partner: ARNT,ARNT,CDKN2A,COPS5,EGLN1,EGLN3,EPO,OS9,RB1,TP53,TP53,VEGFA,VHL,VHL,VHL,ARNT,ARNT,TP53,APEX1,AR,ARNT,ARNT2,ARNTL,CDKN2A,CITED2,COPS5,CREBBP,CSNK2A1,CTNNB1,DAP3,EGLN1,EGLN2,EGLN3,EP300,HDAC1,HIF1AN,HIF3A,HSP90AA1,JUN,MAPK3,MAX,MDM2,MTA1,NAA10,NAA11,NCOA1,NCOA2,NDN,OS9,PER1,PGK1,PSMA7,SEPT9,SP1,SSX4B,STAT3,TP53,TSGA10,VHL,VHLL,APEX1,ARNT,ARNT,ARNTL,CDKN1A,CREBBP,CUL2,DAP3,EP300,GNB2L1,HDAC1,HDAC2,HDAC3,HIF1AN,HSP90AA1,JUN,MDM2,MTA1,Mapk1,NAA10,NCOA1,NR4A1,PSMA7,PSMC3,Per1,SAT1,SAT2,SP1,SSX4,STAT3,TCEB1,TP53,UBC,VHL,Vhl,ZNF197
Protein Size: 826 - Molecular Weight
- 93 kDa
- Gene ID
- 3091
- NCBI Accession
- NM_181054, NP_851397
- UniProt
- Q16665
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