High Mobility Group Box 2 (HMGB2) Peptide
HMGB2
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all HMGB2 products
- HMGB2 (High Mobility Group Box 2 (HMGB2))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-HMGB2 antibody (Catalog #: ARP31939_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- HMGB2 (High Mobility Group Box 2 (HMGB2))
- Synonyms
- HMG2 Peptide, C80539 Peptide, HMG-2 Peptide, Hmg2 Peptide, HIGH MOBILITY GROUP BETA 1 Peptide, HMG BETA 1 Peptide, NFD02 Peptide, NFD2 Peptide, NUCLEOSOME/CHROMATIN ASSEMBLY FACTOR GROUP D 02 Peptide, NUCLEOSOME/CHROMATIN ASSEMBLY FACTOR GROUP D 2 Peptide, high mobility group B2 Peptide, hmgb2 Peptide, hmgb2l Peptide, im:6909096 Peptide, wu:fa20b02 Peptide, zgc:101854 Peptide, wu:fb22b10 Peptide, wu:fc95d12 Peptide, zgc:123215 Peptide, high mobility group box 2 Peptide, high mobility group box 2 S homeolog Peptide, high mobility group B2 Peptide, high mobility group box 2b Peptide, high mobility group box 2a Peptide, HMGB2 Peptide, Hmgb2 Peptide, hmgb2.S Peptide, hmgb2b Peptide, hmgb2a Peptide
- Background
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This protein is a member of the non-histone chromosomal high mobility group family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in the DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: HMG2
Protein Interaction Partner: APEX1,CSNK1A1,GZMA,PGR,POU2F1,POU2F2,POU3F1,POU5F1,PRKDC,RAG1,SET,TP53,AR,CSNK1A1,GZMA,NR3C1,PGR,POU2F2,POU5F1,RAG1,SET
Protein Size: 209 - Molecular Weight
- 24 kDa
- Gene ID
- 3148
- NCBI Accession
- NM_002129, NP_002120
- UniProt
- P26583
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