Heterogeneous Nuclear Ribonucleoprotein F (HNRNPF) (C-Term) Peptide
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- Target See all HNRNPF products
- HNRNPF (Heterogeneous Nuclear Ribonucleoprotein F (HNRNPF))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- TGEADVEFAT HEEAVAAMSK DRANMQHRYI ELFLNSTTGA SNGAYSSQVM
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-HNRNPF Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- HNRNPF (Heterogeneous Nuclear Ribonucleoprotein F (HNRNPF))
- Synonyms
- HNRPF Peptide, OK/SW-cl.23 Peptide, mcs94-1 Peptide, HNRNPF Peptide, Hnrpf Peptide, 4833420I20Rik Peptide, AA407306 Peptide, QtsA-10715 Peptide, hnRNP F Peptide, heterogeneous nuclear ribonucleoprotein F Peptide, HNRNPF Peptide, Hnrnpf Peptide
- Background
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This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and regulate alternative splicing, polyadenylation, and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs which have guanosine-rich sequences. This protein is very similar to the family member hnRPH. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Alias Symbols: HNRPF, MGC110997, OK/SW-cl.23, mcs94-1
Protein Interaction Partner: HNRNPH1,NCBP1,NCBP2,NDRG1,POLR2A,RBFOX1,SUMO4,TXNL4A,ZNF689,HNRNPH1,NCBP1,NCBP2,PRPF40A,SRRM2,SUMO1,SUMO2,TADA2A,TXNL4A,UBC,tat
Protein Size: 415 - Molecular Weight
- 46 kDa
- Gene ID
- 3185
- NCBI Accession
- NM_004966, NP_004957
- UniProt
- P52597
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