Interferon Regulatory Factor 1 (IRF1) Peptide
IRF1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all IRF1 products
- IRF1 (Interferon Regulatory Factor 1 (IRF1))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-IRF1 antibody (Catalog #: ARP38128_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- IRF1 (Interferon Regulatory Factor 1 (IRF1))
- Synonyms
- irf1 Peptide, zgc:136945 Peptide, IRF1 Peptide, irf11 Peptide, zgc:103566 Peptide, IRF-1 Peptide, MAR Peptide, AU020929 Peptide, Irf-1 Peptide, interferon regulatory factor 1 Peptide, interferon regulatory factor 1a Peptide, interferon regulatory factor 1b Peptide, IRF1 Peptide, irf1a Peptide, irf1b Peptide, Irf1 Peptide
- Background
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IRF1 is interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion.IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion.
Alias Symbols: IRF-1, MAR
Protein Interaction Partner: CSNK2A1,CSNK2B,CTDP1,DR1,DRAP1,ERCC3,GTF2F1,MED23,POLR2D,POLR2D,SUB1,TBP,E6,EP300,HMGA1,IRF8,KAT2B,NFKB1,RELA,STAT1,HMGA1,IRF8,KAT2A,KAT2B,STAT1,UBC
Protein Size: 325 - Molecular Weight
- 37 kDa
- Gene ID
- 3659
- NCBI Accession
- NM_002198, NP_002189
- UniProt
- P10914
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