Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1) (Middle Region) Peptide
KCNJ1
Reactivity: Human, Mouse
Host: Synthetic
BP, WB
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- Target See all KCNJ1 products
- KCNJ1 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1))
- Protein Region
- Middle Region
- Origin
- Human, Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-KCNJ1 antibody (Catalog #: ARP35432_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- KCNJ1 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1))
- Synonyms
- KIR1.1 Peptide, ROMK Peptide, ROMK1 Peptide, kir1.1 Peptide, romk1 Peptide, Kcnj Peptide, Kir1.1 Peptide, Romk2 Peptide, kcnj1 Peptide, wu:fl37c05 Peptide, zgc:63534 Peptide, potassium voltage-gated channel subfamily J member 1 Peptide, potassium voltage-gated channel subfamily J member 1 L homeolog Peptide, potassium inwardly-rectifying channel, subfamily J, member 1 Peptide, potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1 Peptide, KCNJ1 Peptide, kcnj1.L Peptide, kcnj1 Peptide, Kcnj1 Peptide, kcnj1a.1 Peptide
- Background
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KCNJ1 has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for KCNJ1.Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis.Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: KIR1.1, ROMK, ROMK1
Protein Interaction Partner: SLC9A3R1,SLC9A3R2,GOLGA3,PRKCD,SGK1,SLC9A3R1,SLC9A3R2,CFTR,IL16,SLC9A3R1,SLC9A3R2
Protein Size: 391 - Molecular Weight
- 45 kDa
- Gene ID
- 3758
- NCBI Accession
- NM_000220, NP_000211
- UniProt
- P48048
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