KH-Type Splicing Regulatory Protein (KHSRP) (Middle Region) Peptide
KHSRP
Reactivity: Human
Host: Synthetic
WB, BP, IHC
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- Target See all KHSRP products
- KHSRP (KH-Type Splicing Regulatory Protein (KHSRP))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Western Blotting (WB), Blocking Peptide (BP), Immunohistochemistry (IHC)
- Sequence
- WEEYYKKQAQ VATGGGPGAP PGSQPDYSAA WAEYYRQQAA YYGQTPGPGG
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-KHSRP Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- KHSRP (KH-Type Splicing Regulatory Protein (KHSRP))
- Synonyms
- FBP2 Peptide, FUBP2 Peptide, KSRP Peptide, 6330409F21Rik Peptide, Fbp2 Peptide, Fubp2 Peptide, Ksrp Peptide, Marta1 Peptide, KHSRP Peptide, VgRBP71 Peptide, fbp2 Peptide, ksrp Peptide, fubp2 Peptide, fc94c12 Peptide, wu:fb25b12 Peptide, wu:fc10e10 Peptide, wu:fc94c12 Peptide, zgc:163038 Peptide, khsrp-b Peptide, KH-type splicing regulatory protein Peptide, KH-type splicing regulatory protein L homeolog Peptide, KH-type splicing regulatory protein S homeolog Peptide, KHSRP Peptide, Khsrp Peptide, khsrp.L Peptide, khsrp Peptide, khsrp.S Peptide
- Background
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KHSRP binds to the dendritic targeting element and may play a role in mRNA trafficking. It is part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. KHSRP mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. It may interact with single-stranded DNA from the far-upstream element (FUSE).It is also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs.
Alias Symbols: FBP2, FUBP2, KSRP, MGC99676
Protein Size: 711 - Molecular Weight
- 73 kDa
- Gene ID
- 8570
- NCBI Accession
- NM_003685, NP_003676
- UniProt
- Q92945
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