Mucosal Vascular Addressin Cell Adhesion Molecule 1 (MADCAM1) (C-Term) Peptide
MADCAM1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all MADCAM1 products
- MADCAM1 (Mucosal Vascular Addressin Cell Adhesion Molecule 1 (MADCAM1))
- Protein Region
- C-Term
- Origin
- Human
- Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- TTSPESPDTT SPESPDTTSQ EPPDTTSPEP PDKTSPEPAP QQGSTHTPRS
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-MADCAM1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MADCAM1 (Mucosal Vascular Addressin Cell Adhesion Molecule 1 (MADCAM1))
- Synonyms
- MACAM1 Peptide, AV211525 Peptide, mucosal vascular addressin cell adhesion molecule 1 Peptide, MADCAM1 Peptide, Madcam1 Peptide
- Background
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The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full-length nature of some variants has not been determined.
Alias Symbols: MACAM1
Protein Interaction Partner: CD44,ITGA4,ITGB7,MADCAM1,ITGB7
Protein Size: 382 - Molecular Weight
- 42 kDa
- Gene ID
- 8174
- NCBI Accession
- NM_130760, NP_570116
- UniProt
- Q13477
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