Mediator Complex Subunit 14 (MED14) (Middle Region) Peptide
MED14
Reactivity: Human
Host: Synthetic
BP, ChIP, WB
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- Target See all MED14 products
- MED14 (Mediator Complex Subunit 14 (MED14))
- Protein Region
- Middle Region
- Origin
- Human
- Source
- Synthetic
- Application
- Blocking Peptide (BP), Chromatin Immunoprecipitation (ChIP), Western Blotting (WB)
- Sequence
- AADREDSPAM ALLLQQFKEN IQDLVFRTKT GKQTRTNAKR KLSDDPCPVE
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-MED14 Antibody(ARP58139_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MED14 (Mediator Complex Subunit 14 (MED14))
- Synonyms
- CG12031 Peptide, Dmel\\CG12031 Peptide, Med14 Peptide, Trap170 Peptide, dTRAP170 Peptide, p160 Peptide, EXLM1 Peptide, crsp150 Peptide, crsp2 Peptide, trap170 Peptide, wu:fd21c05 Peptide, wu:fk28h11 Peptide, CRSP2 Peptide, NV18605 Peptide, CRSP150 Peptide, CSRP Peptide, CXorf4 Peptide, DRIP150 Peptide, RGR1 Peptide, TRAP170 Peptide, 9930001L01Rik Peptide, AU041628 Peptide, Crsp2 Peptide, ENSMUSG00000073278 Peptide, Gm641 Peptide, ORF1 Peptide, RGD1560170 Peptide, Mediator complex subunit 14 Peptide, mediator complex subunit 14 Peptide, mediator of RNA polymerase II transcription subunit 14 Peptide, transcriptional regulation Peptide, MED14 Peptide, med14 Peptide, LOC100113592 Peptide, Med14 Peptide, RGR1 Peptide
- Background
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The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation.
Alias Symbols: CRSP150, CRSP2, CSRP, CXorf4, DRIP150, EXLM1, MGC104513, RGR1, TRAP170
Protein Interaction Partner: ACTN1,ACTN2,AR,HNF4A,MED1,MED29,MED9,NR3C1,STAT2,UACA,BRD4,CDK8,ESR1,ESR2,GATA1,HNF4A,MED1,MED10,MED19,MED21,MED26,MED28,MED29,MED6,MED9,MYC,NR3C1,PPARGC1A,STAT2,VDR
Protein Size: 1454 - Molecular Weight
- 160 kDa
- Gene ID
- 9282
- NCBI Accession
- NM_004229, NP_004220
- UniProt
- O60244
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