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Mediator Complex Subunit 8 (MED8) (N-Term) Peptide

MED8 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN979959
  • Target See all MED8 products
    MED8 (Mediator Complex Subunit 8 (MED8))
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 6
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-MED8 antibody (Catalog #: ARP52440_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    MED8 (Mediator Complex Subunit 8 (MED8))
    Synonyms
    ARC32 Peptide, 2210021A15Rik Peptide, AB041805 Peptide, MNCb-2386 Peptide, zgc:76877 Peptide, med8-a Peptide, mediator complex subunit 8 Peptide, mediator complex subunit 8 L homeolog Peptide, component of RNA polymerase II Peptide, mediator complex subunit Med8 Peptide, MED8 Peptide, Med8 Peptide, med8 Peptide, med8.L Peptide
    Background
    MED8 is a protein that is one of more than 20 subunits of the mediator complex, first identified in S. cerevisiae, that is required for activation of transcription. MED8 also interacts with elongins B and C, and CUL2 and RBX1, to reconstitute a ubiquitin ligase.This gene encodes a protein that is one of more than 20 subunits of the mediator complex, first identified in S. cerevisiae, that is required for activation of transcription. The product of this gene also interacts with elongins B and C, and CUL2 and RBX1, to reconstitute a ubiquitin ligase. Two alternative transcripts encoding different isoforms have been described.

    Alias Symbols: ARC32, MGC17544, MGC19641

    Protein Interaction Partner: ARRB2,CCNC,CDK8,FAM100A,HSPB3,MED1,MED11,MED12,MED17,MED19,MED20,MED22,MED25,MED26,MED27,MED28,MED30,MED31,MED6,MED7,MED8,MED9,PEX14,PHYHIP,SNTA1,TCEB1,THOC7,USP49,ARRB2,HSPB3,MED1,MED10,MED19,MED25,MED26,MED28,MED29,MED30,MED9,PEX14,PHYHIP,THOC7

    Protein Size: 301
    Molecular Weight
    33 kDa
    Gene ID
    112950
    NCBI Accession
    NM_052877, NP_443109
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