Mediator Complex Subunit 8 (MED8) (N-Term) Peptide
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- Target See all MED8 products
- MED8 (Mediator Complex Subunit 8 (MED8))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-MED8 antibody (Catalog #: ARP52440_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MED8 (Mediator Complex Subunit 8 (MED8))
- Synonyms
- ARC32 Peptide, 2210021A15Rik Peptide, AB041805 Peptide, MNCb-2386 Peptide, zgc:76877 Peptide, med8-a Peptide, mediator complex subunit 8 Peptide, mediator complex subunit 8 L homeolog Peptide, component of RNA polymerase II Peptide, mediator complex subunit Med8 Peptide, MED8 Peptide, Med8 Peptide, med8 Peptide, med8.L Peptide
- Background
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MED8 is a protein that is one of more than 20 subunits of the mediator complex, first identified in S. cerevisiae, that is required for activation of transcription. MED8 also interacts with elongins B and C, and CUL2 and RBX1, to reconstitute a ubiquitin ligase.This gene encodes a protein that is one of more than 20 subunits of the mediator complex, first identified in S. cerevisiae, that is required for activation of transcription. The product of this gene also interacts with elongins B and C, and CUL2 and RBX1, to reconstitute a ubiquitin ligase. Two alternative transcripts encoding different isoforms have been described.
Alias Symbols: ARC32, MGC17544, MGC19641
Protein Interaction Partner: ARRB2,CCNC,CDK8,FAM100A,HSPB3,MED1,MED11,MED12,MED17,MED19,MED20,MED22,MED25,MED26,MED27,MED28,MED30,MED31,MED6,MED7,MED8,MED9,PEX14,PHYHIP,SNTA1,TCEB1,THOC7,USP49,ARRB2,HSPB3,MED1,MED10,MED19,MED25,MED26,MED28,MED29,MED30,MED9,PEX14,PHYHIP,THOC7
Protein Size: 301 - Molecular Weight
- 33 kDa
- Gene ID
- 112950
- NCBI Accession
- NM_052877, NP_443109
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