Mesoderm Posterior 2 Homolog (Mesp2) Peptide
Mesp2
Reactivity: Human, Mouse
Host: Synthetic
BP, WB
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- Target See all Mesp2 products
- Mesp2 (Mesoderm Posterior 2 Homolog (Mesp2))
- Origin
- Human, Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-MESP2 antibody (Catalog #: ARP36921_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Mesp2 (Mesoderm Posterior 2 Homolog (Mesp2))
- Synonyms
- bHLHc6 Peptide, SCDO2 Peptide, mesoderm posterior 2 Peptide, mesoderm posterior bHLH transcription factor 2 Peptide, Mesp2 Peptide, MESP2 Peptide
- Background
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Somite boundaries formed during embryogenesis, at the interface between Notch1-activated and -repressed domains. Genetic and biochemical studies indicate that this interface is generated by suppression of Notch activity by mesoderm posterior 2 (Mesp2) through induction of the lunatic fringe gene (Lfng). It is proposed that the oscillation of Notch activity is arrested and translated in the wavefront by Mesp2.
Alias Symbols: bHLHc6
Protein Interaction Partner: Lfng
Protein Size: 370 - Molecular Weight
- 41 kDa
- Gene ID
- 17293
- NCBI Accession
- NM_008589, NP_032615
- UniProt
- O08574
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