Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) (Middle Region) Peptide
MMP3
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all MMP3 products
- MMP3 (Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-MMP3 antibody (Catalog #: ARP42042_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MMP3 (Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))
- Synonyms
- CHDS6 Peptide, MMP-3 Peptide, SL-1 Peptide, STMY Peptide, STMY1 Peptide, STR1 Peptide, SLN-1 Peptide, SLN1 Peptide, STR-1 Peptide, Stmy1 Peptide, Str1 Peptide, MMP10 Peptide, chds6 Peptide, mmp-3 Peptide, mmp13 Peptide, mmp3 Peptide, sl-1 Peptide, stmy Peptide, stmy1 Peptide, str1 Peptide, matrix metallopeptidase 3 Peptide, matrix metallopeptidase 3 (stromelysin 1, progelatinase) Peptide, matrix metallopeptidase 3 L homeolog Peptide, MMP3 Peptide, Mmp3 Peptide, mmp3.L Peptide
- Background
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MMP3 can degrade fibronectin, laminin, gelatins of type I, III, IV, and V, collagens III, IV, X, and IX, and cartilage proteoglycans. MMP3 activates procollagenase.Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC126102, MGC126103, MGC126104, MMP-3, SL-1, STMY, STMY1, STR1, CHDS6
Protein Interaction Partner: ACAN,BCAN,CCL13,CCL2,CCL7,CCL8,DCN,HAPLN1,IGFBP3,MMP3,PLG,SERPINE1,SPOCK1,SPOCK3,SPP1,TIMP1,TIMP3,TNFSF11,BCAN,SPOCK3,TIMP1
Protein Size: 477 - Molecular Weight
- 43 kDa
- Gene ID
- 4314
- NCBI Accession
- NM_002422, NP_002413
- UniProt
- P08254
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