Mitochondrial Ribosomal Protein L45 (MRPL45) (C-Term) Peptide
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- Target See all MRPL45 products
- MRPL45 (Mitochondrial Ribosomal Protein L45 (MRPL45))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- RFGRLMYGQE DVPKDVLEYV VFEKQLTNPY GSWRMHTKIV PPWAPPKQPI
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-MRPL45 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MRPL45 (Mitochondrial Ribosomal Protein L45 (MRPL45))
- Synonyms
- L45mt Peptide, MRP-L45 Peptide, 2600005P05Rik Peptide, AU043542 Peptide, R75241 Peptide, mrlp45 Peptide, mitochondrial ribosomal protein L45 Peptide, mitochondrial ribosomal protein L45 L homeolog Peptide, Mrpl45 Peptide, MRPL45 Peptide, mrpl45.L Peptide
- Background
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Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Pseudogenes corresponding to this gene are found on chromosomes 2p and 17q.
Alias Symbols: MGC11321, L45mt, MRP-L45
Protein Interaction Partner: G3BP1,KBTBD7
Protein Size: 306 - Molecular Weight
- 35 kDa
- Gene ID
- 84311
- NCBI Accession
- NM_032351, NP_115727
- UniProt
- Q9BRJ2
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