Mismatch Repair Protein 2 (MSH2) (N-Term) Peptide
MSH2
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all MSH2 products
- MSH2 (Mismatch Repair Protein 2 (MSH2))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-MSH2 antibody (Catalog #: ARP41351_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MSH2 (Mismatch Repair Protein 2 (MSH2))
- Synonyms
- COCA1 Peptide, FCC1 Peptide, HNPCC Peptide, HNPCC1 Peptide, LCFS2 Peptide, AI788990 Peptide, wu:fc06b02 Peptide, wu:fc13e09 Peptide, zgc:55333 Peptide, ATMSH2 Peptide, MUTS homolog 2 Peptide, msh2 Peptide, mutS homolog 2 Peptide, mutS homolog 2 (E. coli) Peptide, MUTS homolog 2 Peptide, mutS homolog 2 L homeolog Peptide, MutS protein homolog 2 Peptide, MSH2 Peptide, Msh2 Peptide, msh2 Peptide, msh2.L Peptide
- Background
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MSH2 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. MSH2 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: COCA1, FCC1, HNPCC, HNPCC1, LCFS2
Protein Interaction Partner: E2F1,E2F1,E2F3,E2F4,BRCA1,EXO1,EXO1,MAX,MSH3,MSH6,MSH6,ATR,ATRIP,BARD1,CHEK2,CREBBP,EXO1,MAX,MSH3,MSH6,PCNA,SMC1A,AIRE,ATM,ATR,ATRIP,BARD1,BLM,BRCA1,BTBD12,CHEK1,CHEK2,EXO1,MAX,MLH1,MRE11A,MSH2,MSH3,MSH6,MYC,NBN,OTUB1,PCNA,PMS2,PTP4A3,RAD50,RFC1
Protein Size: 934 - Molecular Weight
- 105 kDa
- Gene ID
- 4436
- NCBI Accession
- NM_000251, NP_000242
- UniProt
- P43246
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