NCK Adaptor Protein 1 (NCK1) (N-Term) Peptide
-
- Target See all NCK1 products
- NCK1 (NCK Adaptor Protein 1 (NCK1))
- Protein Region
- N-Term
- Origin
- Human
- Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- PSNYVERKNS ARKASIVKNL KDTLGIGKVK RKPSVPDSAS PADDSFVDPG
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-NCK1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
-
- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- NCK1 (NCK Adaptor Protein 1 (NCK1))
- Synonyms
- NCK Peptide, NCKalpha Peptide, nck-1 Peptide, NCK1 Peptide, 6330586M15Rik Peptide, D230010O13Rik Peptide, Nck Peptide, Nck-1 Peptide, Nck1 Peptide, nck Peptide, nck1-a Peptide, nck1-b Peptide, nckalpha Peptide, NCK adaptor protein 1 Peptide, non-catalytic region of tyrosine kinase adaptor protein 1 Peptide, NCK adaptor protein 1b Peptide, NCK adaptor protein 1 L homeolog Peptide, NCK1 Peptide, Nck1 Peptide, nck1b Peptide, nck1.L Peptide
- Background
-
The protein encoded by this gene is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains. It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS. Alternatively spliced transcript variants encoding different isoforms have been found.
Alias Symbols: MGC12668, NCK, NCKalpha, nck-1
Protein Interaction Partner: ARHGAP32,DNM2,DRD3,DRD4,DRD4,DRD4,FLT1,LCP2,MINK1,PAK1,PDGFRB,RHOU,SOCS1,SOS1,VACVgp200,WAS,ABI1,ABL1,ADAM15,ARHGAP32,ARHGEF7,BCAR1,BLNK,BRK1,CAV2,CBL,CBLB,CD3E,CRK,CSNK1G2,CYFIP2,DCC,DNM1,DOK1,DOK2,DRD3,EGFR,EIF2B2,EIF2S2,EPHB1,EPHB2,FASLG,FLT1,FLT3,FRS2
Protein Size: 377 - Molecular Weight
- 42 kDa
- Gene ID
- 4690
- NCBI Accession
- NM_006153, NP_006144
- UniProt
- P16333
-