Nuclear Receptor Coactivator 3 (NCOA3) (N-Term) Peptide
NCOA3
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all NCOA3 products
- NCOA3 (Nuclear Receptor Coactivator 3 (NCOA3))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- ILKETVRQIR QIKEQGKTIS NDDDVQKADV SSTGQGVIDK DSLGPLLLQA
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-NCOA3 Antibody(ARP32486_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- NCOA3 (Nuclear Receptor Coactivator 3 (NCOA3))
- Synonyms
- NCOA3 Peptide, ACTR Peptide, AIB-1 Peptide, AIB1 Peptide, CAGH16 Peptide, CTG26 Peptide, KAT13B Peptide, RAC3 Peptide, SRC-3 Peptide, SRC3 Peptide, TNRC14 Peptide, TNRC16 Peptide, TRAM-1 Peptide, bHLHe42 Peptide, pCIP Peptide, 2010305B15Rik Peptide, AW321064 Peptide, Actr Peptide, Aib1 Peptide, Rac3 Peptide, Src3 Peptide, Tram-1 Peptide, Tram1 Peptide, p/Cip Peptide, pCip Peptide, actr Peptide, aib-1 Peptide, aib1 Peptide, cagh16 Peptide, ctg26 Peptide, kat13b Peptide, pcip Peptide, rac3 Peptide, src-3 Peptide, src3 Peptide, tnrc14 Peptide, tnrc16 Peptide, tram-1 Peptide, xSRC-3 Peptide, nuclear receptor coactivator 3 Peptide, nuclear receptor coactivator 3 S homeolog Peptide, NCOA3 Peptide, Ncoa3 Peptide, ncoa3.S Peptide
- Background
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NCOA3 is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Two transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein.
Alias Symbols: ACTR, AIB-1, AIB1, CAGH16, CTG26, KAT13B, MGC141848, RAC3, SRC-1, SRC3, TNRC14, TNRC16, TRAM-1, pCIP, SRC-3, bHLHe42
Protein Interaction Partner: CREBBP,ETV1,RXRA,THRB,VDR,PPARA,RARA,CARM1,CREBBP,E2F1,ESR1,GSK3B,RELA,CREBBP,ESR1,KAT2B,RXRB,THRB,AR,BMP6,BMP7,CCND1,CHUK,CREBBP,DDX17,DDX5,E2F1,EP300,ESR1,ESR2,ESRRA,ESRRB,GTF2B,IKBKB,IKBKG,JUN,KAT2B,MAPK1,MAPK14,MMS19,NCOA3,NCOR2,NPAS2,NR1H2,NR1H3,NR1I
Protein Size: 1420 - Molecular Weight
- 155 kDa
- Gene ID
- 8202
- NCBI Accession
- NM_006534, NP_006525
- UniProt
- Q0VF45
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