NADH Dehydrogenase (Ubiquinone) Fe-S Protein 1, 75kDa (NADH-Coenzyme Q Reductase) (NDUFS1) (Middle Region) Peptide
NDUFS1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all NDUFS1 products
- NDUFS1 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 1, 75kDa (NADH-Coenzyme Q Reductase) (NDUFS1))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- TPPGLAREDW KIIRALSEIA GMTLPYDTLD QVRNRLEEVS PNLVRYDDIE
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-NDUFS1 Antibody(ARP56609_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- NDUFS1 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 1, 75kDa (NADH-Coenzyme Q Reductase) (NDUFS1))
- Synonyms
- 5830412M15Rik Peptide, 9930026A05Rik Peptide, CI-75Kd Peptide, CI-75k Peptide, PRO1304 Peptide, NADH dehydrogenase (ubiquinone) Fe-S protein 1 Peptide, NADH:ubiquinone oxidoreductase core subunit S1 Peptide, Ndufs1 Peptide, NDUFS1 Peptide
- Background
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The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in this gene are associated with complex I deficiency.
Alias Symbols: CI-75Kd, MGC26839, PRO1304, CI-75k
Protein Interaction Partner: CASP3,MDH2,CASP3,TNFAIP3
Protein Size: 727 - Molecular Weight
- 77 kDa
- Gene ID
- 4719
- NCBI Accession
- NM_005006, NP_004997
- UniProt
- P28331
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