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NF-kappa-B inhibitor beta (NFKBIB) Peptide

NFKBIB Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN980677
  • Target See all NFKBIB products
    NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))
    Origin
    Human
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-NFKBIB antibody (Catalog #: ARP34505_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))
    Synonyms
    NFKBIB Peptide, IKB-beta Peptide, IKappaBbeta Peptide, IkB Peptide, IkBb Peptide, IKBB Peptide, TRIP9 Peptide, NFKB inhibitor beta Peptide, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta Peptide, NFKBIB Peptide, Nfkbib Peptide
    Background
    Inhibition of NFkappa-B activity by the hepatitis C virus core protein might be related to its physical interaction with and interrupted nuclear localization of IKKbeta. Increased nuclear factor-kappaB (NF-kB) activity in the amnion during labor is associated with an increase in the expression of NF-kBp65 and of the NF-kB binding proteins IkBa, IkBb-1 and IkBb-2. IkappaBbeta may be a novel target for transcription factors of the HMG-box SRY/Sox family and imply a potential role for NF-kappaB/IkappaBbeta in spermatogenesis.

    Alias Symbols: IKBB, TRIP9

    Protein Interaction Partner: IKBKB,MCC,RELA,RELA,BTRC,CD3EAP,CHUK,CUL1,IKBKB,IKBKG,KPNA2,LRPPRC,MCC,MTIF2,NFKB1,NFKB2,NFKBIA,NGFR,NKIRAS1,NKIRAS2,PDCD2,POLR1A,POLR1B,POLR1C,POLR1D,POLR1E,POLR2H,POLR2L,RASAL2,REL,RELA,RXRA,SKP1,BTRC,CHUK,IKBKB,NKIRAS1,REL,RELA,RXRA,Thrb

    Protein Size: 356
    Molecular Weight
    38 kDa
    Gene ID
    4793
    NCBI Accession
    NM_002503, NP_002494
    UniProt
    Q15653
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