Nuclear Transcription Factor Y, beta (NFYB) (Middle Region) Peptide
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- Target See all NFYB products
- NFYB (Nuclear Transcription Factor Y, beta (NFYB))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- EAMKGEKGIG GAVTATDGLS EELTEEAFTN QLPAGLITTD GQQQNVMVYT
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-NFYB Antibody(ARP31262_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- NFYB (Nuclear Transcription Factor Y, beta (NFYB))
- Synonyms
- CBF-A Peptide, CBF-B Peptide, HAP3 Peptide, NF-YB Peptide, NFYB Peptide, nfyb Peptide, zgc:110533 Peptide, zgc:110552 Peptide, hap3 Peptide, cbf-a Peptide, cbf-b Peptide, CBFB Peptide, Nfya Peptide, AA985999 Peptide, Cbf-A Peptide, nuclear transcription factor Y subunit beta Peptide, nuclear transcription factor Y subunit beta L homeolog Peptide, nuclear transcription factor Y, beta b Peptide, nuclear transcription factor Y, beta a Peptide, nuclear transcription factor-Y beta Peptide, NFYB Peptide, nfyb.L Peptide, nfybb Peptide, nfyba Peptide, nfyb Peptide, Nfyb Peptide
- Background
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NFYB is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence, protein sequence alignments and experiments with mutants.
Alias Symbols: CBF-A, CBF-B, HAP3, NF-YB
Protein Interaction Partner: MYC,C1QBP,CEBPZ,CIITA,CNTN2,CSDA,DRAP1,ELF1,EP300,MYC,NFYA,NFYC,SP1,TBP,TP53,TP73,YBX1,CEBPZ,CNTN2,DRAP1,EP300,GRB2,KAT2B,MYC,NFYA,NFYC,TAF11,TAF12,TAF6,TBP,TP53,TP73
Protein Size: 207 - Molecular Weight
- 23 kDa
- Gene ID
- 4801
- NCBI Accession
- NM_006166, NP_006157
- UniProt
- P25208
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