Nuclear Receptor Subfamily 0, Group B, Member 1 (NR0B1) Peptide
NR0B1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all NR0B1 products
- NR0B1 (Nuclear Receptor Subfamily 0, Group B, Member 1 (NR0B1))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-NR0B1 antibody (Catalog #: ARP48004_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- NR0B1 (Nuclear Receptor Subfamily 0, Group B, Member 1 (NR0B1))
- Synonyms
- DAX Peptide, NR0B1 Peptide, dax1 Peptide, AHC Peptide, AHCH Peptide, AHX Peptide, DAX-1 Peptide, DAX1 Peptide, DSS Peptide, GTD Peptide, HHG Peptide, NROB1 Peptide, SRXY2 Peptide, Ahc Peptide, Ahch Peptide, Dax1 Peptide, nuclear receptor subfamily 0 group B member 1 Peptide, nuclear receptor subfamily 0, group B, member 1 Peptide, nuclear receptor subfamily 0 group B member 1 L homeolog Peptide, NR0B1 Peptide, nr0b1 Peptide, nr0b1.L Peptide, Nr0b1 Peptide
- Background
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NR0B1 is a protein that contains a DNA-binding domain. The protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in its gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism.This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism.This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: AHC, AHCH, AHX, DAX-1, DAX1, DSS, GTD, HHG, NROB1, SRXY2
Protein Interaction Partner: AR,COPS2,ESR1,ESR2,ESRRA,NR5A1,NRIP1,PPARG,RORA,SNW1,SREBF1,AR,COPS2,NR5A1,NRIP1,SREBF1
Protein Size: 470 - Molecular Weight
- 52 kDa
- Gene ID
- 190
- NCBI Accession
- NM_000475, NP_000466
- UniProt
- P51843
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