Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1) (Middle Region) Peptide
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- Target See all NR5A1 products
- NR5A1 (Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-NR5A1 antibody (Catalog #: ARP45619_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- NR5A1 (Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1))
- Synonyms
- AD4BP Peptide, ELP Peptide, FTZ1 Peptide, FTZF1 Peptide, POF7 Peptide, SF-1 Peptide, SF1 Peptide, SPGF8 Peptide, SRXY3 Peptide, Ad4BP Peptide, ELP-3 Peptide, Ftz-F1 Peptide, Ftzf1 Peptide, Ad4BP/SF-1 Peptide, Ad4bp Peptide, Sf-1 Peptide, NR5A1 Peptide, sf-1 Peptide, elp Peptide, sf1 Peptide, ftz1 Peptide, ad4bp Peptide, ftzf1 Peptide, SF-1/Ad4BP Peptide, SI:zC167P9.2 Peptide, ff1d Peptide, nr5a2l Peptide, nuclear receptor subfamily 5 group A member 1 Peptide, nuclear receptor subfamily 5, group A, member 1 Peptide, nuclear receptor subfamily 5 group A member 1 L homeolog Peptide, nuclear receptor subfamily 6 group A member 1 Peptide, nuclear receptor subfamily 5, group A, member 1b Peptide, NR5A1 Peptide, Nr5a1 Peptide, nr5a1.L Peptide, nr5a1 Peptide, NR6A1 Peptide, nr5a1b Peptide
- Background
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NR5A1 is an important regulator of steroidogeneisis which is present in human skin and its appendages. It plays a role in regulating p450scc expression with TReP-132 and CBP/p300. The protein encoded by this gene is a transcriptional activator involved in sex determination. The encoded protein binds DNA as a monomer. Defects in this gene are a cause of XY sex reversal with or without adrenal failure as well as adrenocortical insufficiency without ovarian defect. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: AD4BP, ELP, FTZ1, FTZF1, SF-1, SF1, POF7, SPGF8, SRXY3
Protein Interaction Partner: AR,CTNNB1,EDF1,GATA4,GTF2B,JUN,MAPK1,NCOA1,NFKB2,NFYA,NR0B1,NRIP1,PIAS1,PITX1,PNRC2,PROX1,SMARCD3,SOX2,SOX8,SOX9,SP1,TBX19,TRERF1,ZNF653,CTNNB1,EDF1,GATA4,GTF2B,JUN,NCOA1,NR0B1,NRIP1,PITX1,SOX9,SP1,TRERF1,ZNF653
Protein Size: 461 - Molecular Weight
- 52 kDa
- Gene ID
- 2516
- NCBI Accession
- NM_004959, NP_004950
- UniProt
- Q13285
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