Purinergic Receptor P2X, Ligand-Gated Ion Channel, 4 (P2RX4) (N-Term) Peptide
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- Target See all P2RX4 products
- P2RX4 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 4 (P2RX4))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-P2RX4 antibody (Catalog #: ARP35512_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- P2RX4 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 4 (P2RX4))
- Synonyms
- P2X4 Peptide, P2X4R Peptide, AI504491 Peptide, AW555605 Peptide, D5Ertd444e Peptide, p2rx4 Peptide, p2x4 Peptide, wu:fi03f02 Peptide, p2x4r Peptide, p2rx4.2 Peptide, p2xr4.2 Peptide, purinergic receptor P2X 4 Peptide, purinergic receptor P2X, ligand-gated ion channel 4 Peptide, purinergic receptor P2X, ligand-gated ion channel, 4a Peptide, purinergic receptor P2X, ligand gated ion channel, 4 L homeolog Peptide, purinergic receptor P2X, ligand-gated ion channel, 4b Peptide, P2RX4 Peptide, P2rx4 Peptide, p2rx4a Peptide, p2rx4.L Peptide, p2rx4b Peptide
- Background
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P2RX4 is the receptor for ATP that acts as a ligand gated ion channel. This receptor is insensitive to the antagonists PPADS and suramin.The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with high calcium permeability. The main pharmacological distinction between the members of the purinoceptor family is the relative sensitivity to the antagonists suramin and PPADS. The product of this gene has the lowest sensitivity for these antagonists. Multiple alternatively spliced transcript variants have been identified for this gene although their full-length natures have not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: P2X4, P2X4R
Protein Interaction Partner: CDH5,CDH5
Protein Size: 388 - Molecular Weight
- 43 kDa
- Gene ID
- 5025
- NCBI Accession
- NM_002560, NP_002551
- UniProt
- Q99571
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