Poly(A) Polymerase gamma (PAPOLG) (Middle Region) Peptide
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- Target See all PAPOLG products
- PAPOLG (Poly(A) Polymerase gamma (PAPOLG))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PAPOLG antibody (Catalog #: ARP40991_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PAPOLG (Poly(A) Polymerase gamma (PAPOLG))
- Synonyms
- zgc:63762 Peptide, 9630006B20Rik Peptide, poly(A) polymerase gamma Peptide, poly(A) polymerase gamma L homeolog Peptide, papolg Peptide, papolg.L Peptide, PAPOLG Peptide, Papolg Peptide
- Background
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PAPOLG is a member of the poly(A) polymerase family which catalyzes template-independent extension of the 3' end of a DNA/RNA strand. This enzyme shares 60 % identity to the well characterized poly(A) polymerase II (PAPII) at the amino acid level. These two enzymes have similar organization of structural and functional domains. This enzyme is exclusively localized in the nucleus and exhibits both nonspecific and CPSF (cleavage and polyadenylation specificity factor)/AAUAAA-dependent polyadenylation activity.This gene encodes a member of the poly(A) polymerase family which catalyzes template-independent extension of the 3' end of a DNA/RNA strand. This enzyme shares 60 % identity to the well characterized poly(A) polymerase II (PAPII) at the amino acid level. These two enzymes have similar organization of structural and functional domains. This enzyme is exclusively localized in the nucleus and exhibits both nonspecific and CPSF (cleavage and polyadenylation specificity factor)/AAUAAA-dependent polyadenylation activity. This gene is located on chromosome 2 in contrast to the PAPII gene, which is located on chromosome 14.
Alias Symbols: FLJ11805, FLJ12972, FLJ13482, FLJ14187, MGC133307, MGC133308
Protein Size: 736 - Molecular Weight
- 83 kDa
- Gene ID
- 64895
- NCBI Accession
- NM_022894, NP_075045
- UniProt
- Q9BWT3
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