Pre-B-Cell Leukemia Homeobox Interacting Protein 1 (PBXIP1) Peptide
PBXIP1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all PBXIP1 products
- PBXIP1 (Pre-B-Cell Leukemia Homeobox Interacting Protein 1 (PBXIP1))
- Origin
- Human
- Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PBXIP1 antibody (Catalog #: ARP32948_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PBXIP1 (Pre-B-Cell Leukemia Homeobox Interacting Protein 1 (PBXIP1))
- Synonyms
- im:7138234 Peptide, wu:fb12b01 Peptide, zgc:158151 Peptide, 4732463H20Rik Peptide, HPIP Peptide, pre-B-cell leukemia homeobox interacting protein 1b Peptide, PBX homeobox interacting protein 1 Peptide, pre B cell leukemia transcription factor interacting protein 1 Peptide, pbxip1b Peptide, PBXIP1 Peptide, Pbxip1 Peptide
- Background
-
PBXIP1 is the regulator of pre-B-cell leukemia transcription factors (BPXs) function. It inhibits the binding of PBX1-HOX complex to DNA and blocks the transcriptional activity of E2A-PBX1. PBXIP1 tethers estrogen receptor-alpha (ESR1) to microtubules and allows them to influence estrogen receptors-alpha signaling.
Alias Symbols: HPIP
Protein Interaction Partner: CCDC53,CCDC85B,DPPA2,TSNAX,UBQLN4,CCDC53,CCDC85B,DPPA2,TSNAX
Protein Size: 731 - Molecular Weight
- 81 kDa
- Gene ID
- 57326
- NCBI Accession
- NM_020524, NP_065385
- UniProt
- Q96AQ6
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