K(lysine) Acetyltransferase 2B (KAT2B) Peptide
KAT2B
Reactivity: Human, Mouse
Host: Synthetic
BP, WB
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- Target See all KAT2B products
- KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))
- Origin
- Human, Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PCAF antibody (Catalog #: ARP32466_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))
- Synonyms
- PCAF Peptide, pcaf Peptide, si:ch211-1j13.2 Peptide, zgc:161980 Peptide, gb:dq017634 Peptide, im:7156024 Peptide, CAF Peptide, P Peptide, P/CAF Peptide, A930006P13Rik Peptide, AI461839 Peptide, AW536563 Peptide, Pcaf Peptide, p/CAF Peptide, lysine acetyltransferase 2B Peptide, K(lysine) acetyltransferase 2B Peptide, K(lysine) acetyltransferase 2A Peptide, KAT2B Peptide, kat2b Peptide, kat2a Peptide, Kat2b Peptide
- Background
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CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. PCAF associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.
Alias Symbols: P, CAF, PCAF, P/CAF
Protein Interaction Partner: ALB,CTBP1,H3F3A,HIST4H4,NCOA3,PGR,RB1,TACC2,bel-1,tat,ACTN1,ACTN2,AR,BRCA2,CCND1,CDC25B,CIITA,CREBBP,CTBP1,CUX1,DACH2,EP300,ETV1,GATAD2A,GATAD2B,H3F3B,HIPK2,HMGN2,HNF1A,ING1,IRF1,IRF2,IRF7,JDP2,KAT2B,KLF13,MDM2,MECOM,MYOD1,NCOA1,NCOA3,NCOA4,NFE4,NOTCH1,NOTCH3,NPAS2,NR4A1,NRIP1,ONECUT1,RARA,RBPJ,RELA,SATB1,SIRT2,SMAD1,SMAD2,SMAD3,SRCAP,TACC2,TAL1,TCF3,TP53,TP73,TTF1,TWIST1,ARNTL,BRCA2,CCND1,CDC25B,CDK8,CLOCK,CREBBP,CTBP1,CTNNB1,CUX1,EP300,HIST3H3,HIST4H4,HNF1A,ING1,IRF1,IRF2,KLF13,MDM2,MECOM,MED21,MYC,NCOA1,NCOA4,NPAS2,NR4A1,Notch1,ONECUT1,POLR2A,RARA,RBPJ,SMARCB1,SUPT3H,TAF10,TAF5L,TAF9,TCF3,TP53,TRRAP,TTF1,TWIST1,YY1
Protein Size: 832 - Molecular Weight
- 93 kDa
- Gene ID
- 8850
- NCBI Accession
- NM_003884, NP_003875
- UniProt
- Q92831
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