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K(lysine) Acetyltransferase 2B (KAT2B) Peptide

KAT2B Reactivity: Human, Mouse Host: Synthetic BP, WB
Catalog No. ABIN981421
  • Target See all KAT2B products
    KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))
    Origin
    Human, Mouse
    Source
    • 2
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-PCAF antibody (Catalog #: ARP57919_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))
    Synonyms
    PCAF Peptide, pcaf Peptide, si:ch211-1j13.2 Peptide, zgc:161980 Peptide, gb:dq017634 Peptide, im:7156024 Peptide, CAF Peptide, P Peptide, P/CAF Peptide, A930006P13Rik Peptide, AI461839 Peptide, AW536563 Peptide, Pcaf Peptide, p/CAF Peptide, lysine acetyltransferase 2B Peptide, K(lysine) acetyltransferase 2B Peptide, K(lysine) acetyltransferase 2A Peptide, KAT2B Peptide, kat2b Peptide, kat2a Peptide, Kat2b Peptide
    Background
    CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. PCAF associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-749 AC099057.3 17115-17863 750-876 AC099057.3 49416-49542 877-1022 AC099057.3 72346-72491 1023-1115 AC099057.3 76945-77037 1116-1297 AC099057.3 78370-78551 1298-1489 AC099057.3 88679-88870 1490-1596 AC099057.3 91965-92071 1597-1722 AC099057.3 96681-96806 1723-1859 AC099057.3 99751-99887 1860-2068 AC099057.3 102988-103196 2069-2195 AC099057.3 104506-104632 2196-2306 AC099057.3 114025-114135 2307-2450 AC099057.3 117304-117447 2451-2565 AC099057.3 123399-123513 2566-2602 AC099057.3 125046-125082 2603-2666 AC099057.3 125326-125389 2667-2751 AC099057.3 125486-125570 2752-4824 AC099057.3 129415-131487

    Alias Symbols: CAF, KAT2B, P, P/CAF, PCAF

    Protein Interaction Partner: ALB,CTBP1,H3F3A,HIST4H4,NCOA3,PGR,RB1,TACC2,bel-1,tat,ACTN1,ACTN2,AR,BRCA2,CCND1,CDC25B,CIITA,CREBBP,CTBP1,CUX1,DACH2,EP300,ETV1,GATAD2A,GATAD2B,H3F3B,HIPK2,HMGN2,HNF1A,ING1,IRF1,IRF2,IRF7,JDP2,KAT2B,KLF13,MDM2,MECOM,MYOD1,NCOA1,NCOA3,NCOA4,NFE4,NOTCH1,NOTCH3,NPAS2,NR4A1,NRIP1,ONECUT1,RARA,RBPJ,RELA,SATB1,SIRT2,SMAD1,SMAD2,SMAD3,SRCAP,TACC2,TAL1,TCF3,TP53,TP73,TTF1,TWIST1,ARNTL,BRCA2,CCND1,CDC25B,CDK8,CLOCK,CREBBP,CTBP1,CTNNB1,CUX1,EP300,HIST3H3,HIST4H4,HNF1A,ING1,IRF1,IRF2,KLF13,MDM2,MECOM,MED21,MYC,NCOA1,NCOA4,NPAS2,NR4A1,Notch1,ONECUT1,POLR2A,RARA,RBPJ,SMARCB1,SUPT3H,TAF10,TAF5L,TAF9,TCF3,TP53,TRRAP,TTF1,TWIST1,YY1

    Protein Size: 832
    Molecular Weight
    93 kDa
    Gene ID
    8850
    NCBI Accession
    NM_003884, NP_003875
    UniProt
    Q92831
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