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Protocadherin 12 (PCDH12) (Middle Region) Peptide

PCDH12 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN981438
  • Target See all PCDH12 products
    PCDH12 (Protocadherin 12 (PCDH12))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-PCDH12 antibody (Catalog #: ARP47275_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    PCDH12 (Protocadherin 12 (PCDH12))
    Synonyms
    PCDH12 Peptide, VE-cadherin-2 Peptide, VECAD2 Peptide, Pcdh14 Peptide, VE-cad-2 Peptide, protocadherin 12 Peptide, PCDH12 Peptide, Pcdh12 Peptide
    Background
    PCDH12 belongs to the protocadherin protein family, a subfamily of the cadherin superfamily. It consists of an extracellular domain containing 6 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The function of this cellular adhesion protein is undetermined but mouse protocadherin 12 does not bind catenins and appears to have no affect on cell migration or growth.This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 6 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene localizes to the region on chromosome 5 where the protocadherin gene clusters reside. The exon organization of this transcript is similar to that of the gene cluster transcripts, notably the first large exon, but no significant sequence homology exists. The function of this cellular adhesion protein is undetermined but mouse protocadherin 12 does not bind catenins and appears to have no affect on cell migration or growth.

    Alias Symbols: VE-cadherin-2, VECAD2

    Protein Size: 1184
    Molecular Weight
    126 kDa
    Gene ID
    51294
    NCBI Accession
    NM_016580, NP_057664
    UniProt
    Q9NPG4
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